Some of you might not know what this syndrome about. I read about it few days ago and wanted to share to my blog reader. Its a nice info actually and at the same I call it "Awareness". So guys, ready to face the reality....Cyclopia (also cyclocephaly or synophthalmia) is a rare form of
holoprosencephaly and is a
congenital disorder (birth defect) characterized by the failure of the embryonic
prosencephalon to properly divide the
orbits of the eye into two cavities. Its incidence is 1 in 16,000 in born animals, and 1 in 250 in embryos.
Typically, the nose is either missing or replaced with a non-functioning nose in the form of a proboscis. Such a proboscis generally appears above the central eye, and is characteristic of a form of cyclopia called rhinencephaly or rhinocephaly.
Although cyclopia is very rare, several cyclopic human babies are preserved in medical museums (e.g. The Vrolik Museum, Amsterdam). There are also two known cases of children with Down Syndrome being born with one eye.
Some extreme cases of cyclopia have been documented in cats. In such cases, the nose and mouth fail to form, resulting in suffocation shortly after birth.
CAUSES:
Genetic problems or toxins can cause problems in the embryonic forebrain-dividing process.
One highly teratogenic alkaloid toxin that can cause cyclopia is
cyclopamine or 2-deoxyjervine, found in the plant
Veratrum californicum (also known as corn lily or vetch weed). The mistake of ingesting Veratrum californicum while pregnant is often due to the fact that
hellebore, a plant with which it is easily confused, is recommended as a natural treatment for
vomiting,
cramps, and poor circulation, three conditions that are quite common in
pregnant women. Cyclopia occurs in the womb when the protein is inhibited and causes the brain to stay a whole instead of having two distinct hemispheres, which also means one
optic lobe and one
olfactory lobe resulting in one eye.
Notable cases:
An old description of a colt apparently suffering from cyclopia reads:
First, That it had no sign of any Nose in the usual place, nor had it any, in any other place of the Head, unless the double Bagg CC that grew out of the midst of the forehead, were some rudiment of it.
Next, That the two Eyes were united into one Double Eye which was placed just in the middle of the Brow.